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Impaired hypothalamic Fto expression in response to fasting and glucose in obese mice

OBJECTIVE: Recent genome-wide association studies have identified a strong association between obesity and common variants in the fat mass and obesity associated (FTO) gene. FTO has been detected in the hypothalamus, but little is known about its regulation in that particular brain structure. The pr...

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Hlavní autoři: Poritsanos, N J, Lew, P S, Fischer, J, Mobbs, C V, Nagy, J I, Wong, D, Rüther, U, Mizuno, T M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302139/
https://ncbi.nlm.nih.gov/pubmed/23154321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nutd.2011.15
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