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Analysis of the rat JE gene promoter identifies an AP-1 binding site essential for basal expression but not for TPA induction.

We have cloned the immediate-early serum-reponsive JE gene from the rat in order to study the regulation of this gene. We show that sequences of the JE promoter region confer serum-inducibility to a reporter gene. Analysis of the promoter in transient assays reveals that: i) the -141/-88 region is r...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Timmers, H T, Pronk, G J, Bos, J L, van der Eb, A J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1990
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2106664/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.1.23
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