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Purification to apparent homogeneity and partial amino acid sequence of rat liver O6-alkylguanine-DNA-alkyltransferase.

O6-alkylguanine-DNA-alkyltransferase (ATase) activity was increased in rat liver from 80 to 320 fmoles/mg total protein 48 h after administration of 2-acetylaminofluorene at 60 mg/kg body weight. This tissue was used as a source of ATase which was purified by ammonium sulphate precipitation and DNA-...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Wilkinson, M C, Cooper, D P, Southan, C, Potter, P M, Margison, G P
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1990
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330197/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2308819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.1.13
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