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Platelet-derived growth factors and their receptors in normal and malignant hematopoiesis

Platelet-derived growth factors (PDGF) bind to two closely related receptor tyrosine kinases, PDGF receptor α and β, which are encoded by the PDGFRA and PDGFRB genes. Aberrant activation of PDGF receptors occurs in myeloid malignancies associated with hypereosinophilia, due to chromosomal alteration...

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Hlavní autoři: Demoulin, Jean-Baptiste, Montano-Almendras, Carmen P.
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3301440/
https://ncbi.nlm.nih.gov/pubmed/22432087
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