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Premature transcript termination, trans-splicing and DNA repair: a vicious path to cancer

So far, about 800 different chromosomal translocations have been characterized in hemato-malignant and solid tumors. Chromosomal translocations mostly result in the expression of chimeric fusion proteins associated with enhanced proliferation and/or malignant transformation. Here, we demonstrate tha...

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Hlavní autoři: Kowarz, Eric, Merkens, Jennifer, Karas, Michael, Dingermann, Theo, Marschalek, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3301421/
https://ncbi.nlm.nih.gov/pubmed/22432062
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