Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C.

Resistance to activated protein C (APC) is the most prevalent inherited cause of venous thrombosis. The APC resistance phenotype is associated with a single point mutation in the factor V gene, changing Arg506 in the APC cleavage site to a Gln. We have investigated 50 Swedish families with inherited...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Zöller, B, Svensson, P J, He, X, Dahlbäck, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7989612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117623
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!