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The role of lecithin: cholesterol acyltransferase for lipoprotein (a) assembly. Structural integrity of low density lipoproteins is a prerequisite for Lp(a) formation in human plasma.

The composition of lipoproteins in the plasma of patients with LCAT deficiency (LCAT-D) is grossly altered due to the lack of cholesteryl esters which form the core of normal lipoproteins. When plasma from LCAT-D patients and their relatives was examined we found that nine heterozygotes had plasma L...

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Publicado en:J Clin Invest
Autores principales: Steyrer, E, Durovic, S, Frank, S, Giessauf, W, Burger, A, Dieplinger, H, Zechner, R, Kostner, G M
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7989589/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117598
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