High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas.

The development and progression of thyroid tumors is signaled by phenotype-specific mutations of genes involved in growth control. Molecular events associated with undifferentiated thyroid cancer are not known. We examined normal, benign, and malignant thyroid tissue for structural abnormalities of...

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Pubblicato in:	J Clin Invest
Autori principali:	Fagin, J A, Matsuo, K, Karmakar, A, Chen, D L, Tang, S H, Koeffler, H P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116168
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