Biochemical studies of the Saccharomyces cerevisiae Mph1 helicase on junction-containing DNA structures

Saccharomyces cerevisiae Mph1 is a 3–5′ DNA helicase, required for the maintenance of genome integrity. In order to understand the ATPase/helicase role of Mph1 in genome stability, we characterized its helicase activity with a variety of DNA substrates, focusing on its action on junction structures...

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Bibliographic Details
Main Authors: Kang, Young-Hoon, Munashingha, Palinda Ruvan, Lee, Chul-Hwan, Nguyen, Tuan Anh, Seo, Yeon-Soo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300029/
https://ncbi.nlm.nih.gov/pubmed/22090425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr983
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