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Characterization of the kinetic and thermodynamic landscape of RNA folding using a novel application of isothermal titration calorimetry

A novel isothermal titration calorimetry (ITC) method was applied to investigate RNA helical packing driven by the GAAA tetraloop–receptor interaction in magnesium and potassium solutions. Both the kinetics and thermodynamics were obtained in individual ITC experiments, and analysis of the kinetic d...

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Detalhes bibliográficos
Main Authors: Vander Meulen, Kirk A., Butcher, Samuel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300012/
https://ncbi.nlm.nih.gov/pubmed/22058128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr894
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