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Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor.
Thrombin has been implicated in the stimulation of smooth muscle cell (SMC) proliferation that contributes to post angioplasty restenosis. The present studies demonstrated that human alpha-thrombin was a potent and efficacious mitogen for cultured rat aortic SMC, stimulating an increase in 3H-thymid...
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| Publicado en: | J Clin Invest |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1993
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116206 |
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