An isoform-specific mutation in the protein 4.1 gene results in hereditary elliptocytosis and complete deficiency of protein 4.1 in erythrocytes but not in nonerythroid cells.

Multiple protein 4.1 isoforms are expressed in a variety of tissues through complex alternative pre-mRNA splicing events, one function of which is to regulate use of two alternative translation initiation signals. Late erythroid cells express mainly the downstream initiation site for synthesis of pr...

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Bibliographic Details
Main Authors:	Conboy, J G, Chasis, J A, Winardi, R, Tchernia, G, Kan, Y W, Mohandas, N
Format:	Artigo
Language:	Inglês
Published:	1993
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC329997/ https://ncbi.nlm.nih.gov/pubmed/8423235
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An isoform-specific mutation in the protein 4.1 gene results in hereditary elliptocytosis and complete deficiency of protein 4.1 in erythrocytes but not in nonerythroid cells.

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