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Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis

Phenol-soluble modulins are secreted staphylococcal peptides with an amphipathic α-helical structure. Some PSMs are strongly cytolytic toward human neutrophils and represent major virulence determinants during S. aureus skin and blood infection. However, capacities of PSMs to lyse human erythrocytes...

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Detalhes bibliográficos
Main Authors: Cheung, Gordon Y. C., Duong, Anthony C., Otto, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299937/
https://ncbi.nlm.nih.gov/pubmed/22178792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2011.11.013
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