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Characterization of RNA aptamers directed against the nucleocapsid protein of Rift Valley fever virus

Nucleocapsid protein (N) is an essential RNA binding protein in many RNA viruses. During replication, N protein encapsidates viral genomic and antigenomic RNA, but not viral mRNA or other cellular RNAs. To discriminate between different species of RNA in a host cell, it is likely that N interacts wi...

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Detalhes bibliográficos
Main Authors: Ellenbecker, Mary, Sears, Leila, Li, Ping, Lanchy, Jean-Marc, Lodmell, J. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299919/
https://ncbi.nlm.nih.gov/pubmed/22252167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.01.002
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