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Pten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo
Pten, the potent tumor suppressor, is a lipid phosphatase that is best known as a regulator of cell proliferation and cell survival. Here we show that mouse embryos that lack Pten have a striking set of morphogenetic defects, including the failure to correctly specify the anterior-posterior body axi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299915/ https://ncbi.nlm.nih.gov/pubmed/22342906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.02.005 |
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