Mechanosensing by the Primary Cilium: Deletion of Kif3A Reduces Bone Formation Due to Loading

Primary cilia, solitary microtubule-based structures that grow from the centriole and extend into the extracellular space, have increasingly been implicated as sensors of a variety of biochemical and biophysical signals. Mutations in primary cilium-related genes have been linked to a number of rare...

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Autors principals: Temiyasathit, Sara, Tang, W. Joyce, Leucht, Philipp, Anderson, Charles T., Monica, Stefanie D., Castillo, Alesha B., Helms, Jill A., Stearns, Tim, Jacobs, Christopher R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299788/
https://ncbi.nlm.nih.gov/pubmed/22428034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033368
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