Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase.

Nitric oxide provokes vasodilation and inhibits platelet aggregation. We examined the effect of nitric oxide on superoxide anion production by three sources: activated intact neutrophils, xanthine oxidase/hypoxanthine, and the NADPH oxidase. Nitric oxide significantly inhibited the generation of sup...

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Pubblicato in:	J Clin Invest
Autori principali:	Clancy, R M, Leszczynska-Piziak, J, Abramson, S B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1325992/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115929
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