Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy

BACKGROUND: The effective therapies for oral cancer patients of stage III and IV are generally surgical excision and radiation combined with adjuvant chemotherapy using 5-Fu and Cisplatin. However, the five-year survival rate is still less than 30% in Taiwan. Therefore, evaluation of effective drugs...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Ying-Ray, Wu, Wei-Ching, Ji, Wen-Tsai, Chen, Jeff Yi-Fu, Cheng, Ya-Ping, Chiang, Ming-Ko, Chen, Hau-Ren
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299600/
https://ncbi.nlm.nih.gov/pubmed/22283874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-9
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