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Mechanism of resistance to complement-mediated killing of bacteria encoded by the Salmonella typhimurium virulence plasmid gene rck.

We find that pADEO16, a recombinant cosmid carrying the rck gene of the Salmonella typhimurium virulence plasmid, when cloned into either rough or smooth Escherichia coli and Salmonella strains, confers high level resistance to the bactericidal activity of pooled normal human serum. The rck gene enc...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Heffernan, E J, Reed, S, Hackett, J, Fierer, J, Roudier, C, Guiney, D
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1522243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115972
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