Molecular genetics of steroid 5 alpha-reductase 2 deficiency.

Two isozymes of steroid 5 alpha-reductase encoded by separate loci catalyze the conversion of testosterone to dihydrotestosterone. Inherited defects in the type 2 isozyme lead to male pseudohermaphroditism in which affected males have a normal internal urogenital tract but external genitalia resembl...

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Autors principals: Thigpen, A E, Davis, D L, Milatovich, A, Mendonca, B B, Imperato-McGinley, J, Griffin, J E, Francke, U, Wilson, J D, Russell, D W
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC329933/
https://ncbi.nlm.nih.gov/pubmed/1522235
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