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Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis

Deregulated interplay between inflammation and coagulation plays a pivotal role in the pathogenesis of sepsis. Therapeutic approaches that simultaneously target both inflammation and coagulation hold great promise for the treatment of sepsis. Thrombomodulin is an endogenous anticoagulant protein tha...

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Detalhes bibliográficos
Main Authors: Okamoto, Takayuki, Tanigami, Hironobu, Suzuki, Koji, Shimaoka, Motomu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299293/
https://ncbi.nlm.nih.gov/pubmed/22482044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/614545
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