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Endothelium-dependent inhibition of Na(+)-K+ ATPase activity in rabbit aorta by hyperglycemia. Possible role of endothelium-derived nitric oxide.

Hyperglycemia has been shown to diminish Na(+)-K+ ATPase activity in rabbit aorta. To examine the basis for this effect, aortic rings were incubated for 3 h in Krebs-Henseleit solution containing 5.5 or 44 mM glucose, and Na(+)-K+ ATPase activity was then quantified on the basis of ouabain-sensitive...

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Udgivet i:J Clin Invest
Principais autores: Gupta, S, Sussman, I, McArthur, C S, Tornheim, K, Cohen, R A, Ruderman, N B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1325996/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115944
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