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The absence of VPAC(2) leads to aberrant antibody production in Aspergillus fumigatus sensitized and challenged mice
Vasoactive intestinal peptide (VIP) facilitates a “pro-allergy” phenotype when signaling through its G protein-coupled receptor, VPAC(2). We have shown that VPAC(2) knock-out (KO) mice developed an allergic phenotype marked by eosinophilia and elevated serum IgE. Therefore, we hypothesized that the...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299058/ https://ncbi.nlm.nih.gov/pubmed/20923692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.09.022 |
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