Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity.

A major portion of insulin-mediated glucose uptake occurs via the translocation of GLUT 4 glucose transporter proteins from an intracellular depot to the plasma membrane. We have examined gene expression for the GLUT 4 transporter isoform in subcutaneous adipocytes, a classic insulin target cell, to...

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Main Authors: Garvey, W T, Maianu, L, Huecksteadt, T P, Birnbaum, M J, Molina, J M, Ciaraldi, T P
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC329903/
https://ncbi.nlm.nih.gov/pubmed/1999488
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