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Vaccination with Legionella pneumophila membranes induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. Protective immunity independent of the major secretory protein of Legionella pneumophila.

We have examined the capacity of Legionella pneumophila membranes to induce cell-mediated immune responses and protective immunity in a guinea pig model of Legionnaires' disease. Guinea pigs immunized by aerosol with L. pneumophila membranes developed strong cell-mediated immune responses to L. pneu...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Blander, S J, Horwitz, M A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1999485/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115065
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