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Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes. Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion.

We have examined the expression and secretion of endogenous parathyroid hormone-like peptide (PLP) in primary cultures of normal human keratinocytes. In response to growth factors and fetal bovine serum, PLP mRNA expression and immunoreactive PLP release into conditioned medium was rapidly increased...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Kremer, R, Karaplis, A C, Henderson, J, Gulliver, W, Banville, D, Hendy, G N, Goltzman, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329878/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1999499/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115094
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