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Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat

BACKGROUND: In humans, inflammation of either the urinary bladder or the distal colon often results in sensory cross-sensitization between these organs. Limited information is known about the mechanisms underlying this clinical syndrome. Studies with animal models have demonstrated that activation o...

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Main Authors: Xia, Chun-Mei, Gulick, Melisa A, Yu, Sharon J, Grider, John R, Murthy, Karnam S, Kuemmerle, John F, Akbarali, Hamid I, Qiao, Li-Ya
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298724/
https://ncbi.nlm.nih.gov/pubmed/22335898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-30
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