Use of oligonucleotide probes directed against T cell antigen receptor gamma delta variable-(diversity)-joining junctional sequences as a general method for detecting minimal residual disease in acute lymphoblastic leukemias.

To provide a sensitive and generally applicable method to detect clonal cells in acute lymphoblastic leukemias (ALL), we have designed a new strategy based on the polymerase chain reaction (PCR) amplification of the T cell receptor gamma delta gene rearrangements found in most T and B lineage ALLs....

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Macintyre, E A, d'Auriol, L, Duparc, N, Leverger, G, Galibert, F, Sigaux, F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174915/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114951
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