Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway.

The interference of the recombinant HIV-1 glycoproteins gp160 and gp120 with the CD3/T cell antigen receptor (TcR)-mediated activation process has been investigated in the CD4+ diphtheria toxoid-specific human P28D T cell clone. Both glycoproteins clearly inhibit the T cell proliferation induced in...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Cefai, D, Debre, P, Kaczorek, M, Idziorek, T, Autran, B, Bismuth, G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329852/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1979339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114950
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