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Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line

BACKGROUND: Studies have shown the existence of p21 induction in a p53-dependent and -independent pathway. Our previous study indicates that DOX-induced p65 is able to bind the p21 promoter to activate its transactivation in the cells. METHODS: Over-expression and knock-down experiments were perform...

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Detalhes bibliográficos
Main Authors: Zhou, YingQi, Li, Gang, Ji, Yuan, Liu, Chen, Zhu, JingPing, Lu, YanJun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298465/
https://ncbi.nlm.nih.gov/pubmed/22305266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-15
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