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The Evolution of Pepsinogen C Genes in Vertebrates: Duplication, Loss and Functional Diversification

BACKGROUND: Aspartic proteases comprise a large group of enzymes involved in peptide proteolysis. This collection includes prominent enzymes globally categorized as pepsins, which are derived from pepsinogen precursors. Pepsins are involved in gastric digestion, a hallmark of vertebrate physiology....

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Detalles Bibliográficos
Main Authors: Castro, Luís Filipe Costa, Lopes-Marques, Monica, Gonçalves, Odete, Wilson, Jonathan Mark
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298455/
https://ncbi.nlm.nih.gov/pubmed/22427897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032852
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