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Ex Vivo Stretch Reveals Altered Mechanical Properties of Isolated Dystrophin-Deficient Hearts

Duchenne muscular dystrophy (DMD) is a progressive and fatal disease of muscle wasting caused by loss of the cytoskeletal protein dystrophin. In the heart, DMD results in progressive cardiomyopathy and dilation of the left ventricle through mechanisms that are not fully understood. Previous reports...

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Detalhes bibliográficos
Main Authors: Barnabei, Matthew S., Metzger, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298453/
https://ncbi.nlm.nih.gov/pubmed/22427904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032880
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