Mechanism of increased gluconeogenesis in noninsulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism.

To assess the mechanisms responsible for increased gluconeogenesis in noninsulin-dependent diabetes mellitus (NIDDM), we infused [3-14C]lactate, [3-13C]alanine, and [6-3H]glucose in 10 postabsorptive NIDDM subjects and in 9 age- and weight-matched nondiabetic volunteers and measured systemic appeara...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Consoli, A, Nurjhan, N, Reilly, J J, Bier, D M, Gerich, J E
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2254458/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114940
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