Sensitization of head and neck cancer to cisplatin through the use of a novel curcumin analogue

OBJECTIVES: Signal transducer and activator of transcription (STAT) proteins regulate key cellular fate decisions including proliferation and apoptosis. Over-expression of STAT3 induces tumor growth. We hypothesized that a novel small molecule inhibitor derived from curcumin (FLLL32) that targets ST...

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Detalhes bibliográficos
Main Authors: Abuzeid, Waleed M., Davis, Samantha, Tang, Alice, Saunders, Lindsay, Brenner, J. Chadwick, Lin, Jiayuh, Fuchs, James R., Light, Emily, Bradford, Carol R., Prince, Mark E.P., Carey, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298372/
https://ncbi.nlm.nih.gov/pubmed/21576562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archoto.2011.63
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