Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution.

Transforming growth factor beta 1 (TGF-beta 1) is a key regulator of cell growth and differentiation. Under normal physiological conditions, it is made as a biologically latent complex whose significance is unknown. Previous work has indicated that active TGF-beta 1 has a very short plasma half-life...

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Bibliografiske detaljer
Main Authors: Wakefield, L M, Winokur, T S, Hollands, R S, Christopherson, K, Levinson, A D, Sporn, M B
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC329834/
https://ncbi.nlm.nih.gov/pubmed/2254455
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