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β1D chain increases α7β1 integrin and laminin and protects against sarcolemmal damage in mdx mice
The dystrophin–glycoprotein complex connects myofibers with extracellular matrix laminin. In Duchenne muscular dystrophy, this linkage system is absent and the integrity of muscle fibers is compromised. One potential therapy for addressing muscular dystrophy is to augment the amount of α7β1 integrin...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298282/ https://ncbi.nlm.nih.gov/pubmed/22180459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr596 |
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