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Distal enhancers upstream of the Charcot-Marie-Tooth type 1A disease gene PMP22

Myelin insulates axons in the peripheral nervous system to allow rapid propagation of action potentials, and proper myelination requires the precise regulation of genes encoding myelin proteins, including PMP22. The correct gene dosage of PMP22 is critical; a duplication of PMP22 is the most common...

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Autors principals: Jones, Erin A., Brewer, Megan H., Srinivasan, Rajini, Krueger, Courtney, Sun, Guannan, Charney, Kira N., Keles, Sunduz, Antonellis, Anthony, Svaren, John
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298281/
https://ncbi.nlm.nih.gov/pubmed/22180461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr595
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