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Conserved Mechanisms of Mycobacterium marinum Pathogenesis within the Environmental Amoeba Acanthamoeba castellanii

Mycobacterium marinum is a waterborne mycobacterial pathogen. Due to their common niche, protozoa likely represent natural hosts for M. marinum. We demonstrate that the ESX-1 secretion system is required for M. marinum pathogenesis and that M. marinum utilizes actin-based motility in amoebae. Theref...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kennedy, George M., Morisaki, J. Hiroshi, DiGiuseppe Champion, Patricia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298165/
https://ncbi.nlm.nih.gov/pubmed/22247144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06965-11
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