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Improved risk prediction for Crohn's disease with a multi-locus approach

Genome-wide association studies have identified numerous loci demonstrating genome-wide significant association with Crohn's disease. However, when many single nucleotide polymorphisms (SNPs) have weak-to-moderate disease risks, genetic risk prediction models based only on those markers that pa...

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Библиографические подробности
Главные авторы: Kang, Jia, Kugathasan, Subra, Georges, Michel, Zhao, Hongyu, Cho, Judy H.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298027/
https://ncbi.nlm.nih.gov/pubmed/21427131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr116
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