At physiologic albumin/oleate concentrations oleate uptake by isolated hepatocytes, cardiac myocytes, and adipocytes is a saturable function of the unbound oleate concentration. Uptake kinetics are consistent with the conventional theory.

To reexamine the role of albumin in cellular uptake of long chain fatty acids, we measured [3H]oleate uptake by isolated hepatocytes, adipocytes, and cardiac myocytes from incubations containing oleate/albumin complexes at molar ratios from 0.01:1 to 2:1. For each ratio the uptake was studied over a...

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Vydáno v:J Clin Invest
Hlavní autoři: Sorrentino, D, Robinson, R B, Kiang, C L, Berk, P D
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1989
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329794/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2794064/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114301
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