Sequence and exon-intron organization of the DNA encoding the alpha I domain of human spectrin. Application to the study of mutations causing hereditary elliptocytosis.

We have determined the exon-intron organization and the nucleotide sequence of the exons and their flanking intronic DNA in cloned genomic DNA that encodes the first 526 amino acids of the alpha I domain of the human red cell spectrin polypeptide chain. From the gene sequence we designed oligonucleo...

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Detalhes bibliográficos
Main Authors: Sahr, K E, Tobe, T, Scarpa, A, Laughinghouse, K, Marchesi, S L, Agre, P, Linnenbach, A J, Marchesi, V T, Forget, B G
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329784/
https://ncbi.nlm.nih.gov/pubmed/2794061
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