Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk

BACKGROUND: Telomeres protect chromosomal ends, shorten with cellular division, and signal cellular senescence but unchecked telomere attrition can lead to telomere dysfunction, upregulation of telomerase, and carcinogenesis. Shorter telomeres in peripheral blood leukocytes (PBLs) have been associat...

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Main Authors: Terry, Kathryn L., Tworoger, Shelley S., Vitonis, Allison F., Wong, Jason, Titus-Ernstoff, Linda, De Vivo, Immaculata, Cramer, Daniel W.
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297716/
https://ncbi.nlm.nih.gov/pubmed/22267287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0867
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