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Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk

BACKGROUND: Telomeres protect chromosomal ends, shorten with cellular division, and signal cellular senescence but unchecked telomere attrition can lead to telomere dysfunction, upregulation of telomerase, and carcinogenesis. Shorter telomeres in peripheral blood leukocytes (PBLs) have been associat...

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Autors principals: Terry, Kathryn L., Tworoger, Shelley S., Vitonis, Allison F., Wong, Jason, Titus-Ernstoff, Linda, De Vivo, Immaculata, Cramer, Daniel W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297716/
https://ncbi.nlm.nih.gov/pubmed/22267287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0867
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