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Hemoglobin A1C above threshold levels are associated with decreased β-cell function in overweight Latino youth

OBJECTIVE: To determine, in an overweight pediatric population, if an A1C-determined high risk, pre-diabetic state (A1C ≥6.0–6.4%) is associated with decreased insulin sensitivity and β-cell dysfunction, known factors in the pathogenesis of type 2 diabetes. STUDY DESIGN: We divided 206 healthy overw...

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Autors principals: Toledo-Corral, Claudia M., Vargas, Lisa G., Goran, Michael I., Weigensberg, Marc J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297692/
https://ncbi.nlm.nih.gov/pubmed/22137671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2011.10.024
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