Lipocytes from normal rat liver release a neutral metalloproteinase that degrades basement membrane (type IV) collagen.

We report a proteinase that degrades basement-membrane (type IV) collagen and is produced by the liver. Its cellular source is lipocytes (fat-storing or Ito cells). Lipocytes were isolated from normal rat liver and established in primary culture. The cells synthesize and secrete a neutral proteinase...

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Publié dans:	J Clin Invest
Auteurs principaux:	Arthur, M J, Friedman, S L, Roll, F J, Bissell, D M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2551922/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114270
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