Exploring the Complexity of the HIV-1 Fitness Landscape

Although fitness landscapes are central to evolutionary theory, so far no biologically realistic examples for large-scale fitness landscapes have been described. Most currently available biological examples are restricted to very few loci or alleles and therefore do not capture the high dimensionali...

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Main Authors: Kouyos, Roger D., Leventhal, Gabriel E., Hinkley, Trevor, Haddad, Mojgan, Whitcomb, Jeannette M., Petropoulos, Christos J., Bonhoeffer, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297571/
https://ncbi.nlm.nih.gov/pubmed/22412384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002551
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