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Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion

BACKGROUND: We recently provided evidence that HIV-1 enters HeLa-derived TZM-bl and lymphoid CEMss cells by fusing with endosomes, whereas its fusion with the plasma membrane does not proceed beyond the lipid mixing step. The mechanism of restriction of HIV-1 fusion at the cell surface and/or the fa...

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Detalhes bibliográficos
Main Authors: de la Vega, Michelle, Marin, Mariana, Kondo, Naoyuki, Miyauchi, Kosuke, Kim, Yuri, Epand, Raquel F, Epand, Richard M, Melikyan, Gregory B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297528/
https://ncbi.nlm.nih.gov/pubmed/22145853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-99
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