Cl- secretion induced by bile salts. A study of the mechanism of action based on a cultured colonic epithelial cell line.

When applied to the basolateral (serosal) side of the T84 colonic epithelial monolayer, taurodeoxycholate caused net Cl- secretion in a dose-dependent manner with a threshold effect observed at 0.2 mM. In contrast, when applied to the apical (luminal) surface, concentrations of taurodeoxycholate bel...

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Pubblicato in:	J Clin Invest
Autori principali:	Dharmsathaphorn, K, Huott, P A, Vongkovit, P, Beuerlein, G, Pandol, S J, Ammon, H V
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2547841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114257
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