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Platelet receptor-mediated factor X activation by factor IXa. High-affinity factor IXa receptors induced by factor VIII are deficient on platelets in Scott syndrome.

We have studied factor IXa binding and factor X activation with normal platelets and with platelets obtained from a patient with a bleeding disorder and an isolated deficiency of platelet procoagulant activity termed Scott syndrome. In the absence of factor VIIIa and factor X, normal, thrombin-treat...

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Pubblicato in:J Clin Invest
Autori principali: Ahmad, S S, Rawala-Sheikh, R, Ashby, B, Walsh, P N
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2547839/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114242
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