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Activation of clones producing self-reactive antibodies by foreign antigen and antiidiotype antibody carrying the internal image of the antigen.

Because we found in previous work that a high fraction of antibodies exhibiting various specificities bound to glutamic acid 50-tyrosine50 homopolymer (GT) and expressed pGAT cross-reactive idiotype (IdX), we studied the activation of clones producing multireactive antibodies in 1-mo-old MRL/lpr and...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Bailey, N C, Fidanza, V, Mayer, R, Mazza, G, Fougereau, M, Bona, C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2760212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114232
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