Synergetic Effect of Recoverin and Calmodulin on Regulation of Rhodopsin Kinase

Phosphorylation of photoactivated rhodopsin by rhodopsin kinase (RK or GRK1), a first step of the phototransduction cascade turnoff, is under the control of Ca(2+)/recoverin. Here, we demonstrate that calmodulin, a ubiquitous Ca(2+)-sensor, can inhibit RK, though less effectively than recoverin does...

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Hlavní autoři: Grigoriev, Ilya I., Senin, Ivan I., Tikhomirova, Natalya K., Komolov, Konstantin E., Permyakov, Sergei E., Zernii, Evgeni Yu., Koch, Karl-Wilhelm, Philippov, Pavel P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2012
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296934/
https://ncbi.nlm.nih.gov/pubmed/22408603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00028
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